K(Ca)3.1-dependent uptake of the cytotoxic DNA-binding dye Hoechst 33258 into cancerous but not healthy cervical cells

The poor and nonselective penetration of current chemotherapeutics across the plasma membranes of cancer cells, which is necessary for the targeted disruption of the intracellular machinery, remains a major pharmaceutical challenge. In several cell types, including mast cells and macrophages, exposu...

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Detalles Bibliográficos
Autores principales: Bukhari, Maurish, Deng, Han, Sipes, Darren, Ruane-Foster, Marisa, Purdy, Kayla, Woodworth, Craig D., Sur, Shantanu, Samways, Damien S.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948979/
https://www.ncbi.nlm.nih.gov/pubmed/33199365
http://dx.doi.org/10.1074/jbc.RA120.013997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948979/
https://www.ncbi.nlm.nih.gov/pubmed/33199365
http://dx.doi.org/10.1074/jbc.RA120.013997

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