A structural basis for lithium and substrate binding of an inositide phosphatase

Inositol polyphosphate 1-phosphatase (INPP1) is a prototype member of metal-dependent/lithium-inhibited phosphomonoesterase protein family defined by a conserved three-dimensional core structure. Enzymes within this family function in distinct pathways including inositide signaling, gluconeogenesis,...

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Detalles Bibliográficos
Autores principales: Dollins, D. Eric, Xiong, Jian-Ping, Endo-Streeter, Stuart, Anderson, David E., Bansal, Vinay S., Ponder, Jay W., Ren, Yi, York, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948987/
https://www.ncbi.nlm.nih.gov/pubmed/33172890
http://dx.doi.org/10.1074/jbc.RA120.014057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948987/
https://www.ncbi.nlm.nih.gov/pubmed/33172890
http://dx.doi.org/10.1074/jbc.RA120.014057

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