Cargando…

A structural basis for lithium and substrate binding of an inositide phosphatase

Inositol polyphosphate 1-phosphatase (INPP1) is a prototype member of metal-dependent/lithium-inhibited phosphomonoesterase protein family defined by a conserved three-dimensional core structure. Enzymes within this family function in distinct pathways including inositide signaling, gluconeogenesis,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dollins, D. Eric, Xiong, Jian-Ping, Endo-Streeter, Stuart, Anderson, David E., Bansal, Vinay S., Ponder, Jay W., Ren, Yi, York, John D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948987/ https://www.ncbi.nlm.nih.gov/pubmed/33172890 http://dx.doi.org/10.1074/jbc.RA120.014057

Ejemplares similares

Nuclear Inositides and Inositide-Dependent Signaling Pathways in Myelodysplastic Syndromes
por: Xian, Jie, et al.
Publicado: (2020)

The Inositide Signaling Pathway As a Target for Treating Gastric Cancer and Colorectal Cancer
por: Kim, Hong Jun, et al.
Publicado: (2016)

Muscle-specific inositide phosphatase (MIP/MTMR14) is reduced with age and its loss accelerates skeletal muscle aging process by altering calcium homeostasis
por: Romero-Suarez, Sandra, et al.
Publicado: (2010)

Response of high-risk MDS to azacitidine and lenalidomide is impacted by baseline and acquired mutations in a cluster of three inositide-specific genes
por: Follo, Matilde Y., et al.
Publicado: (2019)

Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme
por: Fedoryshchak, Roman O, et al.
Publicado: (2020)

Sulfation of glycosaminoglycans depends on the catalytic activity of lithium-inhibited phosphatase BPNT2 in vitro
por: Eisele, Brynna S., et al.
Publicado: (2021)

Structural basis for substrate discrimination and integrin binding by autotaxin
por: Hausmann, Jens, et al.
Publicado: (2011)

Spinophilin directs Protein Phosphatase 1 specificity by blocking substrate binding sites
por: Ragusa, Michael J., et al.
Publicado: (2010)

Understanding the molecular basis of substrate binding specificity of PTB domains
por: Sain, Neetu, et al.
Publicado: (2016)

The antiproton target station on the basis of lithium lenses
por: Bayanov, B F, et al.
Publicado: (1980)

Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters
por: Picollo, Alessandra, et al.
Publicado: (2009)

Structural basis of redox-dependent substrate binding of protein disulfide isomerase
por: Yagi-Utsumi, Maho, et al.
Publicado: (2015)

Structural Basis of Glycerophosphodiester Recognition by the Mycobacterium tuberculosis Substrate-Binding Protein UgpB
por: Fenn, Jonathan S., et al.
Publicado: (2019)

Protein kinase- and lipase inhibitors of inositide metabolism deplete IP(7) indirectly in pancreatic β-cells: Off-target effects on cellular bioenergetics and direct effects on IP6K activity
por: Rajasekaran, Subu Surendran, et al.
Publicado: (2018)

Substrate Binding Mode and Molecular Basis of a Specificity Switch in Oxalate Decarboxylase
por: Zhu, Wen, et al.
Publicado: (2016)

Direct Determination of Phosphatase Activity from Physiological Substrates in Cells
por: Ren, Zhongyuan, et al.
Publicado: (2015)

Phosphoproteomic Approaches for Identifying Phosphatase and Kinase Substrates
por: DeMarco, Andrew G., et al.
Publicado: (2023)

Covalent Docking Predicts Substrates for Haloalkanoate Dehalogenase Superfamily Phosphatases
por: London, Nir, et al.
Publicado: (2014)

Structural Basis of Response Regulator Dephosphorylation by Rap Phosphatases
por: Parashar, Vijay, et al.
Publicado: (2011)

Structural Basis of Rap Phosphatase Inhibition by Phr Peptides
por: Gallego del Sol, Francisca, et al.
Publicado: (2013)

Oxidative decomposition mechanisms of lithium carbonate on carbon substrates in lithium battery chemistries
por: Cao, Deqing, et al.
Publicado: (2022)

Structural Basis of Substrate Binding in WsaF, a Rhamnosyltransferase from Geobacillus stearothermophilus
por: Steiner, Kerstin, et al.
Publicado: (2010)

Determinants for Substrate Specificity of Protein Phosphatase 2A
por: Slupe, Andrew M., et al.
Publicado: (2011)

Phosphotyrosine Substrate Sequence Motifs for Dual Specificity Phosphatases
por: Zhao, Bryan M., et al.
Publicado: (2015)

Structure of 3-mercaptopropionic acid dioxygenase with a substrate analog reveals bidentate substrate binding at the iron center
por: York, Nicholas J., et al.
Publicado: (2021)

Coupling substrate-trapping with proximity-labeling to identify protein tyrosine phosphatase PTP1B signaling networks
por: Bonham, Christopher A., et al.
Publicado: (2023)

Structural basis of protein phosphatase 2A stable latency
por: Jiang, Li, et al.
Publicado: (2013)

Combining free energy calculations with tailored enzyme activity assays to elucidate substrate binding of a phospho-lysine phosphatase
por: Hauser, Anett, et al.
Publicado: (2020)

Allosteric substrate switching in a voltage sensing lipid phosphatase
por: Grimm, Sasha S., et al.
Publicado: (2016)

Reinterpretation of the substrate specificity of the voltage-sensing phosphatase during dimerization
por: Kruse, Martin, et al.
Publicado: (2019)

Substrate recognition determinants of human eIF2α phosphatases
por: Hodgson, George, et al.
Publicado: (2021)

Plk4 Is a Novel Substrate of Protein Phosphatase 5
por: Ábrahám, Edit, et al.
Publicado: (2023)

Investigating the basis of substrate recognition in the pC221 relaxosome
por: Caryl, Jamie A, et al.
Publicado: (2006)

Structural basis for the specificity of PPM1H phosphatase for Rab GTPases
por: Waschbüsch, Dieter, et al.
Publicado: (2021)

Structural Basis for Substrate Specificity of Mammalian Neuraminidases
por: Smutova, Victoria, et al.
Publicado: (2014)

Molecular Basis for Polyketide Ketoreductase–Substrate Interactions
por: Zhao, Shiji, et al.
Publicado: (2020)

The Histochemical Demonstration of Secretory Capillaries in the Pancreas with the Aid of Substrate Specific Phosphatases
por: Wachstein, Max, et al.
Publicado: (1959)

Characterization of New Substrates Targeted By Yersinia Tyrosine Phosphatase YopH
por: de la Puerta, María Luisa, et al.
Publicado: (2009)

Novel Live Alkaline Phosphatase Substrate for Identification of Pluripotent Stem Cells
por: Singh, Upinder, et al.
Publicado: (2012)

Kizuna is a novel mitotic substrate for CDC25B phosphatase
por: Thomas, Yann, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_uvjptos3h8takr3haff5bbuj8q