Mechanotransduction via a TRPV4-Rac1 signaling axis plays a role in multinucleated giant cell formation

Multinucleated giant cells are formed by the fusion of macrophages and are a characteristic feature in numerous pathophysiological conditions including the foreign body response (FBR). Foreign body giant cells (FBGCs) are inflammatory and destructive multinucleated macrophages and may cause damage a...

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Detalles Bibliográficos
Autores principales: Arya, Rakesh K., Goswami, Rishov, Rahaman, Shaik O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948992/
https://www.ncbi.nlm.nih.gov/pubmed/33262217
http://dx.doi.org/10.1074/jbc.RA120.014597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948992/
https://www.ncbi.nlm.nih.gov/pubmed/33262217
http://dx.doi.org/10.1074/jbc.RA120.014597

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