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Mechanotransduction via a TRPV4-Rac1 signaling axis plays a role in multinucleated giant cell formation

Multinucleated giant cells are formed by the fusion of macrophages and are a characteristic feature in numerous pathophysiological conditions including the foreign body response (FBR). Foreign body giant cells (FBGCs) are inflammatory and destructive multinucleated macrophages and may cause damage a...

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Detalles Bibliográficos
Autores principales:	Arya, Rakesh K., Goswami, Rishov, Rahaman, Shaik O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948992/ https://www.ncbi.nlm.nih.gov/pubmed/33262217 http://dx.doi.org/10.1074/jbc.RA120.014597

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