Chemokine receptor CXCR4 oligomerization is disrupted selectively by the antagonist ligand IT1t

CXCR4, a member of the family of chemokine-activated G protein–coupled receptors, is widely expressed in immune response cells. It is involved in both cancer development and progression as well as viral infection, notably by HIV-1. A variety of methods, including structural information, have suggest...

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Detalles Bibliográficos
Autores principales: Ward, Richard J., Pediani, John D., Marsango, Sara, Jolly, Richard, Stoneman, Michael R., Biener, Gabriel, Handel, Tracy M., Raicu, Valerică, Milligan, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949023/
https://www.ncbi.nlm.nih.gov/pubmed/33268380
http://dx.doi.org/10.1074/jbc.RA120.016612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949023/
https://www.ncbi.nlm.nih.gov/pubmed/33268380
http://dx.doi.org/10.1074/jbc.RA120.016612

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