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DNA damage promotes ER stress resistance through elevation of unsaturated phosphatidylcholine in Caenorhabditis elegans

DNA damage triggers the cellular adaptive response to arrest proliferation and repair DNA damage; when damage is too severe to be repaired, apoptosis is initiated to prevent the spread of genomic insults. However, how cells endure DNA damage to maintain cell function remains largely unexplored. By u...

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Detalles Bibliográficos
Autores principales: Deng, Jianhui, Bai, Xue, Tang, Haiqing, Pang, Shanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949029/
https://www.ncbi.nlm.nih.gov/pubmed/33208465
http://dx.doi.org/10.1074/jbc.RA120.016083