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Biochemical and crystallographic investigations into isonitrile formation by a nonheme iron-dependent oxidase/decarboxylase

The isonitrile moiety is found in marine sponges and some microbes, where it plays a role in processes such as virulence and metal acquisition. Until recently only one route was known for isonitrile biosynthesis, a condensation reaction that brings together a nitrogen atom of l-Trp/l-Tyr with a carb...

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Detalles Bibliográficos
Autores principales: Jonnalagadda, Rohan, Del Rio Flores, Antonio, Cai, Wenlong, Mehmood, Rimsha, Narayanamoorthy, Maanasa, Ren, Chaoxiang, Zaragoza, Jan Paulo T., Kulik, Heather J., Zhang, Wenjun, Drennan, Catherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949033/
https://www.ncbi.nlm.nih.gov/pubmed/33361191
http://dx.doi.org/10.1074/jbc.RA120.015932