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A cell-nonautonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism

Caloric restriction (CR) improves health span and life span of organisms ranging from yeast to mammals. Understanding the mechanisms involved will uncover future interventions for aging-associated diseases. In budding yeast, Saccharomyces cerevisiae, CR is commonly defined by reduced glucose in the...

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Detalles Bibliográficos
Autores principales: Enriquez-Hesles, Elisa, Smith, Daniel L., Maqani, Nazif, Wierman, Margaret B., Sutcliffe, Matthew D., Fine, Ryan D., Kalita, Agata, Santos, Sean M., Muehlbauer, Michael J., Bain, James R., Janes, Kevin A., Hartman, John L., Hirschey, Matthew D., Smith, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949035/
https://www.ncbi.nlm.nih.gov/pubmed/33243834
http://dx.doi.org/10.1074/jbc.RA120.015402