Zinc transporter mutations linked to acrodermatitis enteropathica disrupt function and cause mistrafficking

ZIP4 is a representative member of the Zrt-/Irt-like protein (ZIP) transporter family and responsible for zinc uptake from diet. Loss-of-function mutations of human ZIP4 (hZIP4) drastically reduce zinc absorption, causing a life-threatening autosomal recessive disorder, acrodermatitis enteropathica...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuliyev, Eziz, Zhang, Chi, Sui, Dexin, Hu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949036/
https://www.ncbi.nlm.nih.gov/pubmed/33837739
http://dx.doi.org/10.1016/j.jbc.2021.100269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949036/
https://www.ncbi.nlm.nih.gov/pubmed/33837739
http://dx.doi.org/10.1016/j.jbc.2021.100269

Ejemplares similares