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The noncoding RNA BC200 associates with polysomes to positively regulate mRNA translation in tumor cells

BC200 is a noncoding RNA elevated in a broad spectrum of tumor cells that is critical for cell viability, invasion, and migration. Overexpression studies have implicated BC200 and the rodent analog BC1 as negative regulators of translation in both cell-based and in vitro translation assays. Although...

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Detalles Bibliográficos
Autores principales: Booy, Evan P., Gussakovsky, Daniel, Choi, Taegi, McKenna, Sean A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949042/
https://www.ncbi.nlm.nih.gov/pubmed/33410401
http://dx.doi.org/10.1074/jbc.RA120.015775