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SOCS3–microtubule interaction via CLIP-170 and CLASP2 is critical for modulation of endothelial inflammation and lung injury

Proinflammatory cytokines such as IL-6 induce endothelial cell (EC) barrier disruption and trigger an inflammatory response in part by activating the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway. The protein suppressor of cytokine signaling-3 (SOCS3) is a negative...

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Detalles Bibliográficos
Autores principales: Karki, Pratap, Ke, Yunbo, Zhang, Chen-Ou, Li, Yue, Tian, Yufeng, Son, Sophia, Yoshimura, Akihiko, Kaibuchi, Kozo, Birukov, Konstantin G., Birukova, Anna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949054/
https://www.ncbi.nlm.nih.gov/pubmed/33372035
http://dx.doi.org/10.1074/jbc.RA120.014232