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SOCS3–microtubule interaction via CLIP-170 and CLASP2 is critical for modulation of endothelial inflammation and lung injury
Proinflammatory cytokines such as IL-6 induce endothelial cell (EC) barrier disruption and trigger an inflammatory response in part by activating the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway. The protein suppressor of cytokine signaling-3 (SOCS3) is a negative...
Autores principales: | Karki, Pratap, Ke, Yunbo, Zhang, Chen-Ou, Li, Yue, Tian, Yufeng, Son, Sophia, Yoshimura, Akihiko, Kaibuchi, Kozo, Birukov, Konstantin G., Birukova, Anna A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949054/ https://www.ncbi.nlm.nih.gov/pubmed/33372035 http://dx.doi.org/10.1074/jbc.RA120.014232 |
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