Cu, Fe, and Zn isotope ratios in murine Alzheimer's disease models suggest specific signatures of amyloidogenesis and tauopathy

Alzheimer’s disease (AD) is characterized by accumulation of tau and amyloid-beta in the brain, and recent evidence suggests a correlation between associated protein aggregates and trace elements, such as copper, iron, and zinc. In AD, a distorted brain redox homeostasis and complexation by amyloid-...

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Detalles Bibliográficos
Autores principales: Solovyev, Nikolay, El-Khatib, Ahmed H., Costas-Rodríguez, Marta, Schwab, Karima, Griffin, Elizabeth, Raab, Andrea, Platt, Bettina, Theuring, Franz, Vogl, Jochen, Vanhaecke, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949056/
https://www.ncbi.nlm.nih.gov/pubmed/33453282
http://dx.doi.org/10.1016/j.jbc.2021.100292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949056/
https://www.ncbi.nlm.nih.gov/pubmed/33453282
http://dx.doi.org/10.1016/j.jbc.2021.100292

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