T cell receptor–dependent S-acylation of ZAP-70 controls activation of T cells

ZAP-70 is a tyrosine kinase essential for T cell immune responses. Upon engagement of the T cell receptor (TCR), ZAP-70 is recruited to the specialized plasma membrane domains, becomes activated, and is released to phosphorylate its laterally segregated targets. A shift in ZAP-70 distribution at the...

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Detalles Bibliográficos
Autores principales: Tewari, Ritika, Shayahati, Bieerkehazhi, Fan, Ying, Akimzhanov, Askar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949058/
https://www.ncbi.nlm.nih.gov/pubmed/33482200
http://dx.doi.org/10.1016/j.jbc.2021.100311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949058/
https://www.ncbi.nlm.nih.gov/pubmed/33482200
http://dx.doi.org/10.1016/j.jbc.2021.100311

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