Cargando…

T cell receptor–dependent S-acylation of ZAP-70 controls activation of T cells

ZAP-70 is a tyrosine kinase essential for T cell immune responses. Upon engagement of the T cell receptor (TCR), ZAP-70 is recruited to the specialized plasma membrane domains, becomes activated, and is released to phosphorylate its laterally segregated targets. A shift in ZAP-70 distribution at the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tewari, Ritika, Shayahati, Bieerkehazhi, Fan, Ying, Akimzhanov, Askar M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949058/ https://www.ncbi.nlm.nih.gov/pubmed/33482200 http://dx.doi.org/10.1016/j.jbc.2021.100311

Ejemplares similares

Regulation of T cell function by protein S-acylation
por: West, Savannah J., et al.
Publicado: (2022)

Reconstitution of T cell receptor signaling in ZAP-70-deficient cells by retroviral transduction of the ZAP-70 gene
Publicado: (1996)

Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT
por: Lo, Wan-Lin, et al.
Publicado: (2018)

Dynamic S-acylation of the ER-resident protein stromal interaction molecule 1 (STIM1) is required for store-operated Ca(2+) entry
por: Kodakandla, Goutham, et al.
Publicado: (2022)

Dephosphorylation accelerates the dissociation of ZAP70 from the T cell receptor
por: Goyette, Jesse, et al.
Publicado: (2022)

Intrinsic Disorder in the T Cell Receptor Creates Cooperativity and Controls ZAP70 Binding
por: Clemens, Lara, et al.
Publicado: (2021)

ZAP-70 Tyrosine Kinase Is Required for LFA-1–dependent T Cell Migration
por: Soede, Ron D.M., et al.
Publicado: (1998)

Immunomodulatory drugs activate NK cells via both Zap-70 and cereblon-dependent pathways
por: Hideshima, Teru, et al.
Publicado: (2020)

The Structural Basis for Activation and Inhibition of ZAP-70 Kinase Domain
por: Huber, Roland G., et al.
Publicado: (2015)

ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity
Publicado: (1995)

ZAP-70 Shapes the Immune Microenvironment in B Cell Malignancies
por: Chen, Jingyu, et al.
Publicado: (2020)

Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes
Publicado: (1996)

RhoH Regulates Subcellular Localization of ZAP-70 and Lck in T Cell Receptor Signaling
por: Chae, Hee-Don, et al.
Publicado: (2010)

ZAP-70 Regulates Autoimmune Arthritis via Alterations in T Cell Activation and Apoptosis
por: Kugyelka, Réka, et al.
Publicado: (2019)

T and NK cell lymphoma cell lines do not rely on ZAP-70 for survival
por: de Mel, Sanjay, et al.
Publicado: (2022)

Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes
Publicado: (1995)

Destabilizing the autoinhibitory conformation of Zap70 induces up-regulation of inhibitory receptors and T cell unresponsiveness
por: Hsu, Lih-Yun, et al.
Publicado: (2017)

Quantitative and Temporal Requirements Revealed for Zap-70 Catalytic Activity During T Cell Development
por: Au-Yeung, Byron B., et al.
Publicado: (2014)

ZAP-70 Restoration in Mice by In Vivo Thymic Electroporation
por: Irla, Magali, et al.
Publicado: (2008)

Survivin Regulates Bad Gene Expression by Binding to Its Promoter and Modulates Cell Cycle and Apoptosis in Esophageal Carcinoma Cell
por: Chen, Yan, et al.
Publicado: (2021)

Gefitinib targets ZAP-70-expressing chronic lymphocytic leukemia cells and inhibits B-cell receptor signaling
por: Dielschneider, R F, et al.
Publicado: (2014)

Engineering a Dual Small Molecule Gated ZAP70 Switch in T Cells
por: Wong, Nicole M. L., et al.
Publicado: (2018)

Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination
por: Hu, Hongbo, et al.
Publicado: (2016)

Inhibition of ZAP-70 Kinase Activity via an Analog-sensitive Allele Blocks T Cell Receptor and CD28 Superagonist Signaling
por: Levin, Susan E., et al.
Publicado: (2008)

The Shc Family Protein Adaptor, Rai, Negatively Regulates T Cell Antigen Receptor Signaling by Inhibiting ZAP-70 Recruitment and Activation
por: Ferro, Micol, et al.
Publicado: (2011)

Restricting Zap70 Expression to CD4(+)CD8(+) Thymocytes Reveals a T Cell Receptor–dependent Proofreading Mechanism Controlling the Completion of Positive Selection
por: Liu, Xiaolong, et al.
Publicado: (2003)

Zap70 Regulates TCR-Mediated Zip6 Activation at the Immunological Synapse
por: Kim, Bonah, et al.
Publicado: (2021)

An evolutionary divergent thermodynamic brake in ZAP-70 fine-tunes the kinetic proofreading in T cells
por: Gangopadhyay, Kaustav, et al.
Publicado: (2022)

The CD3 chains of the T cell antigen receptor associate with the ZAP-70 tyrosine kinase and are tyrosine phosphorylated after receptor stimulation
Publicado: (1993)

Light-Controlled Affinity Purification of Protein Complexes Exemplified by the Resting ZAP70 Interactome
por: Hörner, Maximilian, et al.
Publicado: (2019)

Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex
Publicado: (1995)

Inhibition of T Cell Receptor Activation by Semi-Synthetic Sesquiterpene Lactone Derivatives and Molecular Modeling of Their Interaction with Glutathione and Tyrosine Kinase ZAP-70
por: Khlebnikov, Andrei I., et al.
Publicado: (2019)

ZAP-70 Association with T Cell Receptor ζ (TCRζ): Fluorescence Imaging of Dynamic Changes upon Cellular Stimulation
por: Sloan-Lancaster, Joanne, et al.
Publicado: (1998)

mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse
por: Thumkeo, D., et al.
Publicado: (2020)

RANTES induces tyrosine kinase activity of stably complexed p125FAK and ZAP-70 in human T cells
Publicado: (1996)

GTPase-activating protein Rasal1 associates with ZAP-70 of the TCR and negatively regulates T-cell tumor immunity
por: Thaker, Youg Raj, et al.
Publicado: (2019)

Kinetic proofreading through the multi-step activation of the ZAP70 kinase underlies early T cell ligand discrimination
por: Voisinne, Guillaume, et al.
Publicado: (2022)

A Novel ZAP-70 Dependent FRET Based Biosensor Reveals Kinase Activity at both the Immunological Synapse and the Antisynapse
por: Randriamampita, Clotilde, et al.
Publicado: (2008)

ZAP70, too little, too much can lead to autoimmunity
por: Ashouri, Judith F., et al.
Publicado: (2021)

Distinct roles for Syk and ZAP-70 during early thymocyte development
por: Palacios, Emil H., et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_bdek7eeu8vn1pm190fkc055265