A second mechanism employed by artemisinins to suppress Plasmodium falciparum hinges on inhibition of hematin crystallization

Malaria is a pervasive disease that affects millions of lives each year in equatorial regions of the world. During the erythrocytic phase of the parasite life cycle, Plasmodium falciparum invades red blood cells, where it catabolizes hemoglobin and sequesters the released toxic heme as innocuous hem...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Wenchuan, Balta, Victoria A., West, Rachel, Newlin, Katy N., Miljanić, Ognjen Š., Sullivan, David J., Vekilov, Peter G., Rimer, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949059/
https://www.ncbi.nlm.nih.gov/pubmed/33239360
http://dx.doi.org/10.1074/jbc.RA120.016115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949059/
https://www.ncbi.nlm.nih.gov/pubmed/33239360
http://dx.doi.org/10.1074/jbc.RA120.016115

Ejemplares similares