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A second mechanism employed by artemisinins to suppress Plasmodium falciparum hinges on inhibition of hematin crystallization
Malaria is a pervasive disease that affects millions of lives each year in equatorial regions of the world. During the erythrocytic phase of the parasite life cycle, Plasmodium falciparum invades red blood cells, where it catabolizes hemoglobin and sequesters the released toxic heme as innocuous hem...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949059/ https://www.ncbi.nlm.nih.gov/pubmed/33239360 http://dx.doi.org/10.1074/jbc.RA120.016115 |