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Adaptive mutations promote hepatitis C virus assembly by accelerating core translocation to the endoplasmic reticulum

The envelopment of hepatitis C virus (HCV) is believed to occur primarily in the endoplasmic reticulum (ER)-associated membrane, and the translocation of viral Core protein from lipid droplets (LDs) to the ER is essential for the envelopment of viral particles. However, the factors involved are not...

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Detalles Bibliográficos
Autores principales: Zheng, Fuxiang, Li, Ni, Xu, Yi, Zhou, Yuanping, Li, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949066/
https://www.ncbi.nlm.nih.gov/pubmed/33144326
http://dx.doi.org/10.1074/jbc.RA120.016010