Maedi–visna virus Vif protein uses motifs distinct from HIV-1 Vif to bind zinc and the cofactor required for A3 degradation

The mammalian apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3 or A3) family of cytidine deaminases restrict viral infections by mutating viral DNA and impeding reverse transcription. To overcome this antiviral activity, most lentiviruses express a viral accessory protein c...

Descripción completa

Detalles Bibliográficos
Autores principales: Knecht, Kirsten M., Hu, Yingxia, Rubene, Diana, Cook, Matthew, Ziegler, Samantha J., Jónsson, Stefán R., Xiong, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949081/
https://www.ncbi.nlm.nih.gov/pubmed/33465707
http://dx.doi.org/10.1074/jbc.RA120.015828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949081/
https://www.ncbi.nlm.nih.gov/pubmed/33465707
http://dx.doi.org/10.1074/jbc.RA120.015828

Ejemplares similares