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Maedi–visna virus Vif protein uses motifs distinct from HIV-1 Vif to bind zinc and the cofactor required for A3 degradation

The mammalian apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3 or A3) family of cytidine deaminases restrict viral infections by mutating viral DNA and impeding reverse transcription. To overcome this antiviral activity, most lentiviruses express a viral accessory protein c...

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Detalles Bibliográficos
Autores principales:	Knecht, Kirsten M., Hu, Yingxia, Rubene, Diana, Cook, Matthew, Ziegler, Samantha J., Jónsson, Stefán R., Xiong, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949081/ https://www.ncbi.nlm.nih.gov/pubmed/33465707 http://dx.doi.org/10.1074/jbc.RA120.015828

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