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Mutant BIN1-Dynamin 2 complexes dysregulate membrane remodeling in the pathogenesis of centronuclear myopathy

Membrane remodeling is required for dynamic cellular processes such as cell division, polarization, and motility. BAR domain proteins and dynamins are key molecules in membrane remodeling that work together for membrane deformation and fission. In striated muscles, sarcolemmal invaginations termed T...

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Detalles Bibliográficos
Autores principales: Fujise, Kenshiro, Okubo, Mariko, Abe, Tadashi, Yamada, Hiroshi, Nishino, Ichizo, Noguchi, Satoru, Takei, Kohji, Takeda, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949082/
https://www.ncbi.nlm.nih.gov/pubmed/33187981
http://dx.doi.org/10.1074/jbc.RA120.015184