Lactate fluxes mediated by the monocarboxylate transporter-1 are key determinants of the metabolic activity of beige adipocytes

Activation of energy-dissipating brown/beige adipocytes represents an attractive therapeutic strategy against metabolic disorders. While lactate is known to induce beiging through the regulation of Ucp1 gene expression, the role of lactate transporters on beige adipocytes' ongoing metabolic act...

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Detalles Bibliográficos
Autores principales: Lagarde, Damien, Jeanson, Yannick, Barreau, Corinne, Moro, Cedric, Peyriga, Lindsay, Cahoreau, Edern, Guissard, Christophe, Arnaud, Emmanuelle, Galinier, Anne, Bouzier-Sore, Anne-Karine, Pellerin, Luc, Chouchani, Edward T., Pénicaud, Luc, Ader, Isabelle, Portais, Jean-Charles, Casteilla, Louis, Carrière, Audrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949083/
https://www.ncbi.nlm.nih.gov/pubmed/33268383
http://dx.doi.org/10.1074/jbc.RA120.016303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949083/
https://www.ncbi.nlm.nih.gov/pubmed/33268383
http://dx.doi.org/10.1074/jbc.RA120.016303

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