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Genomic determinants implicated in the glucocorticoid-mediated induction of KLF9 in pulmonary epithelial cells

Ligand-activated glucocorticoid receptor (GR) elicits variable glucocorticoid-modulated transcriptomes in different cell types. However, some genes, including Krüppel-like factor 9 (KLF9), a putative transcriptional repressor, demonstrate conserved responses. We show that glucocorticoids induce KLF9...

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Detalles Bibliográficos
Autores principales: Mostafa, Mahmoud M., Bansal, Akanksha, Michi, Aubrey N., Sasse, Sarah K., Proud, David, Gerber, Anthony N., Newton, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949084/
https://www.ncbi.nlm.nih.gov/pubmed/33184061
http://dx.doi.org/10.1074/jbc.RA120.015755