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O-linked N-acetylglucosamine transferase (OGT) regulates pancreatic α-cell function in mice
The nutrient sensor O-GlcNAc transferase (OGT) catalyzes posttranslational addition of O-GlcNAc onto target proteins, influencing signaling pathways in response to cellular nutrient levels. OGT is highly expressed in pancreatic glucagon-secreting cells (α-cells), which secrete glucagon in response t...
Autores principales: | Essawy, Ahmad, Jo, Seokwon, Beetch, Megan, Lockridge, Amber, Gustafson, Eric, Alejandro, Emilyn U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949098/ https://www.ncbi.nlm.nih.gov/pubmed/33460647 http://dx.doi.org/10.1016/j.jbc.2021.100297 |
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