Poly(ADP-ribose) polymerase 1 regulates mitochondrial DNA repair in an NAD-dependent manner

Mitochondrial DNA is located in organelle that house essential metabolic reactions and contains high reactive oxygen species. Therefore, mitochondrial DNA suffers more oxidative damage than its nuclear counterpart. Formation of a repair enzyme complex is beneficial to DNA repair. Recent studies have...

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Detalles Bibliográficos
Autores principales: Herrmann, Geoffrey K., Russell, William K., Garg, Nisha J., Yin, Y. Whitney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949115/
https://www.ncbi.nlm.nih.gov/pubmed/33482196
http://dx.doi.org/10.1016/j.jbc.2021.100309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949115/
https://www.ncbi.nlm.nih.gov/pubmed/33482196
http://dx.doi.org/10.1016/j.jbc.2021.100309

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