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Aminoglycerophospholipid flipping and P4-ATPases in Toxoplasma gondii

Lipid flipping in the membrane bilayers is a widespread eukaryotic phenomenon that is catalyzed by assorted P4-ATPases. Its occurrence, mechanism, and importance in apicomplexan parasites have remained elusive, however. Here we show that Toxoplasma gondii, an obligate intracellular parasite with hig...

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Detalles Bibliográficos
Autores principales: Chen, Kai, Günay-Esiyok, Özlem, Klingeberg, Melissa, Marquardt, Stephan, Pomorski, Thomas Günther, Gupta, Nishith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949121/
https://www.ncbi.nlm.nih.gov/pubmed/33485966
http://dx.doi.org/10.1016/j.jbc.2021.100315