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Potentiation of B2 receptor signaling by AltB2R, a newly identified alternative protein encoded in the human bradykinin B2 receptor gene

Recent functional and proteomic studies in eukaryotes (www.openprot.org) predict the translation of alternative open reading frames (AltORFs) in mature G-protein-coupled receptor (GPCR) mRNAs, including that of bradykinin B2 receptor (B2R). Our main objective was to determine the implication of a ne...

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Detalles Bibliográficos
Autores principales: Gagnon, Maxime, Savard, Martin, Jacques, Jean-François, Bkaily, Ghassan, Geha, Sameh, Roucou, Xavier, Gobeil, Fernand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949122/
https://www.ncbi.nlm.nih.gov/pubmed/33497625
http://dx.doi.org/10.1016/j.jbc.2021.100329