Ceramide synthase 2 deletion decreases the infectivity of HIV-1

The lipid composition of HIV-1 virions is enriched in sphingomyelin (SM), but the roles that SM or other sphingolipids (SLs) might play in the HIV-1 replication pathway have not been elucidated. In human cells, SL levels are regulated by ceramide synthase (CerS) enzymes that produce ceramides, which...

Descripción completa

Detalles Bibliográficos
Autores principales: Barklis, Eric, Alfadhli, Ayna, Kyle, Jennifer E., Bramer, Lisa M., Bloodsworth, Kent J., Barklis, Robin Lid, Leier, Hans C., Petty, R. Max, Zelnik, Iris D., Metz, Thomas O., Futerman, Anthony H., Tafesse, Fikadu G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949126/
https://www.ncbi.nlm.nih.gov/pubmed/33515546
http://dx.doi.org/10.1016/j.jbc.2021.100340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949126/
https://www.ncbi.nlm.nih.gov/pubmed/33515546
http://dx.doi.org/10.1016/j.jbc.2021.100340

Ejemplares similares