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Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo

Neural cell adhesion molecules 1 (NCAM1) and 2 (NCAM2) belong to the cell adhesion molecules of the immunoglobulin superfamily and have been shown to regulate formation, maturation, and maintenance of synapses. NCAM1 and NCAM2 undergo proteolysis, but the identity of all the proteases involved and h...

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Detalles Bibliográficos
Autores principales: Kim, WonHee, Watanabe, Hiroto, Lomoio, Selene, Tesco, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949136/
https://www.ncbi.nlm.nih.gov/pubmed/33548223
http://dx.doi.org/10.1016/j.jbc.2021.100372