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The molecular basis of OH-PCB estrogen receptor activation

Polychlorinated bisphenols (PCBs) continue to contaminate food chains globally where they concentrate in tissues and disrupt the endocrine systems of species throughout the ecosphere. Hydroxylated PCBs (OH-PCBs) are major PCB metabolites and high-affinity inhibitors of human estrogen sulfotransferas...

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Detalles Bibliográficos
Autores principales: Wang, Ting, Cook, Ian, Leyh, Thomas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949139/
https://www.ncbi.nlm.nih.gov/pubmed/33524392
http://dx.doi.org/10.1016/j.jbc.2021.100353