Cargando…

SIRT1 stabilizes extrachromosomal gene amplification and contributes to repeat-induced gene silencing

Sirtuin 1 (SIRT1) is a protein deacetylase that maintains genome stability by preventing the activation of latent replication origins. Amplified genes in cancer cells localize on either extrachromosomal double minutes (DMs) or the chromosomal homogeneously staining region. Previously, we found that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Taniguchi, Ryonosuke, Utani, Koichi, Thakur, Bhushan, Ishine, Kazuho, Aladjem, Mirit I., Shimizu, Noriaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949162/ https://www.ncbi.nlm.nih.gov/pubmed/33539925 http://dx.doi.org/10.1016/j.jbc.2021.100356

Ejemplares similares

Extra View: Sirt1 Acts As A Gatekeeper Of Replication Initiation To Preserve Genomic Stability.
por: Utani, Koichi, et al.
Publicado: (2018)

Gene Amplification and the Extrachromosomal Circular DNA
por: Shimizu, Noriaki
Publicado: (2021)

Epigenetic Repeat-Induced Gene Silencing in the Chromosomal and Extrachromosomal Contexts in Human Cells
por: Mitsuda, Sho-hei, et al.
Publicado: (2016)

Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability
por: Utani, Koichi, et al.
Publicado: (2017)

Amplification of a plasmid bearing a mammalian replication initiation region in chromosomal and extrachromosomal contexts
por: Harada, Seiyu, et al.
Publicado: (2011)

Repeat induces not only gene silencing, but also gene activation in mammalian cells
por: Ogaki, Yusuke, et al.
Publicado: (2020)

Amplification and Quantitation of Telomeric Extrachromosomal Circles
por: Robinson, Nathaniel J., et al.
Publicado: (2023)

SIRT1/PARP1 crosstalk: connecting DNA damage and metabolism
por: Luna, Augustin, et al.
Publicado: (2013)

Cloning and Characterization of a Human Genomic Sequence that Alleviates Repeat-Induced Gene Silencing
por: Fukuma, Miki, et al.
Publicado: (2016)

SIRT1 Prevents R-Loops during Chronological Aging by Modulating DNA Replication at rDNA Loci
por: Thakur, Bhushan L., et al.
Publicado: (2023)

Extrachromosomal oncogene amplification drives tumor evolution and genetic heterogeneity
por: Turner, Kristen M., et al.
Publicado: (2017)

Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma
por: Vogt, Nicolas, et al.
Publicado: (2014)

OTEH-12. Assessing Adaptive Responses to Loss of Extrachromosomal DNA Amplification
por: Berezovsky, Artem, et al.
Publicado: (2021)

Selective Entrapment of Extrachromosomally Amplified DNA by Nuclear Budding and Micronucleation during S Phase
por: Shimizu, Noriaki, et al.
Publicado: (1998)

Regulation of cell cycle drivers by Cullin-RING ubiquitin ligases
por: Jang, Sang-Min, et al.
Publicado: (2020)

Tracking of microinjected DNA in live cells reveals the intracellular behavior and elimination of extrachromosomal genetic material
por: Shimizu, Noriaki, et al.
Publicado: (2005)

Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers
por: Kim, Hoon, et al.
Publicado: (2020)

Survey of extrachromosomal circular DNA derived from plant satellite repeats
por: Navrátilová, Alice, et al.
Publicado: (2008)

Extrachromosomal circles of satellite repeats and 5S ribosomal DNA in human cells
por: Cohen, Sarit, et al.
Publicado: (2010)

Engineering rules that minimize germline silencing of transgenes in simple extrachromosomal arrays in C. elegans
por: Aljohani, Mohammed D., et al.
Publicado: (2020)

Dynamics of replication origin over-activation
por: Fu, Haiqing, et al.
Publicado: (2021)

Extrachromosomal circular DNA as a vehicle to gene transfer in plants
por: Pereira, Lara, et al.
Publicado: (2023)

Inhibiting homologous recombination decreases extrachromosomal amplification but has no effect on intrachromosomal amplification in methotrexate‐resistant colon cancer cells
por: Cai, Mengdi, et al.
Publicado: (2018)

How transcription proceeds in a large artificial heterochromatin in human cells
por: Utani, Koh-ichi, et al.
Publicado: (2009)

Extrachromosomal circular DNA-based amplification and transmission of herbicide resistance in crop weed Amaranthus palmeri
por: Koo, Dal-Hoe, et al.
Publicado: (2018)

Gene targeting in mosquito cells: a demonstration of 'knockout' technology in extrachromosomal gene arrays
por: Eggleston, Paul, et al.
Publicado: (2001)

DNA replication profiling by molecular combing on single DNA fibers
por: Fu, Haiqing, et al.
Publicado: (2022)

Formation of Extrachromosomal Circular DNA from Long Terminal Repeats of Retrotransposons in Saccharomyces cerevisiae
por: Møller, Henrik D., et al.
Publicado: (2015)

Amplification of a Zygosaccharomyces bailii DNA Segment in Wine Yeast Genomes by Extrachromosomal Circular DNA Formation
por: Galeote, Virginie, et al.
Publicado: (2011)

Generation of Micronuclei during Interphase by Coupling between Cytoplasmic Membrane Blebbing and Nuclear Budding
por: Utani, Koh-ichi, et al.
Publicado: (2011)

Role of Genes and their Relationship to Extrachromosomal Factors in the Development of Mammary Gland Tumours in Mice
por: Heston, W. E.
Publicado: (1948)

The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin
por: Jang, Sang-Min, et al.
Publicado: (2018)

Circuit diagrams for biological networks
por: Kohn, Kurt W, et al.
Publicado: (2006)

Visualization and quantitative analysis of extrachromosomal telomere-repeat DNA in individual human cells by Halo-FISH
por: Komosa, Martin, et al.
Publicado: (2015)

An efficient protein production system via gene amplification on a human artificial chromosome and the chromosome transfer to CHO cells
por: Ohira, Takahito, et al.
Publicado: (2019)

Dissection of the Beta-Globin Replication-Initiation Region Reveals Specific Requirements for Replicator Elements during Gene Amplification
por: Okada, Naoya, et al.
Publicado: (2013)

METB-01. EXTRACHROMOSOMAL DNA IS ASSOCIATED WITH ONCOGENE AMPLIFICATION AND POOR SURVIVAL ACROSS MULTIPLE PEDIATRIC CANCER TYPES
por: Sridhar, Sunita, et al.
Publicado: (2023)

Encounters in Three Dimensions: How Nuclear Topology Shapes Genome Integrity
por: Sebastian, Robin, et al.
Publicado: (2021)

SIRT1 Inhibition Alleviates Gene Silencing in Fragile X Mental Retardation Syndrome
por: Biacsi, Rea, et al.
Publicado: (2008)

The Extrachromosomal EAST Protein of Drosophila Can Associate with Polytene Chromosomes and Regulate Gene Expression
por: Wasser, Martin, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_8hb4802psb3rrl8m6jkl7r71j2