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Inhibition of nitric oxide production of activated mice peritoneal macrophages is independent of the Toxoplasma gondii strain

BACKGROUND: Toxoplasma gondii causes toxoplasmosis and is controlled by activated macrophages. However, infection of macrophages by tachyzoites induces TGF-β signaling (TGF-s) inhibiting nitric oxide (NO) production. NO inhibition may be a general escape mechanism of distinct T. gondii strains. OBJE...

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Detalles Bibliográficos
Autores principales: Damasceno-Sá, João Cláudio, de Souza, Fernanda Silva, dos Santos, Thiago Alves Teixeira, de Oliveira, Fábio Conceição, da Silva, Maria de Fátima Sarro, Dias, Raul Ramos Furtado, de Souza, Wanderley, Arnholdt, Andrea Cristina Veto, Seabra, Sergio Henrique, DaMatta, Renato Augusto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949196/
https://www.ncbi.nlm.nih.gov/pubmed/33729328
http://dx.doi.org/10.1590/0074-02760200417