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CXCR6 deficiency impairs cancer vaccine efficacy and CD8(+) resident memory T-cell recruitment in head and neck and lung tumors
BACKGROUND: Resident memory T lymphocytes (T(RM)) are located in tissues and play an important role in immunosurveillance against tumors. The presence of T(RM) prior to treatment or their induction is associated to the response to anti-Programmed cell death protein 1 (PD-1)/Programmed death-ligand 1...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949477/ https://www.ncbi.nlm.nih.gov/pubmed/33692218 http://dx.doi.org/10.1136/jitc-2020-001948 |