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N-cadherin inhibitor creates a microenvironment that protect TILs from immune checkpoints and Treg cells
BACKGROUND: Few patients with prostate cancer benefit from current immunotherapies. Therefore, we aimed to explore new strategies to change this paradigm. METHODS: Human tissues, cell lines and in vivo experiments were used to determine whether and how N-cadherin impacts the production of programmed...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949480/ https://www.ncbi.nlm.nih.gov/pubmed/33692219 http://dx.doi.org/10.1136/jitc-2020-002138 |