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N-cadherin inhibitor creates a microenvironment that protect TILs from immune checkpoints and Treg cells

BACKGROUND: Few patients with prostate cancer benefit from current immunotherapies. Therefore, we aimed to explore new strategies to change this paradigm. METHODS: Human tissues, cell lines and in vivo experiments were used to determine whether and how N-cadherin impacts the production of programmed...

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Detalles Bibliográficos
Autores principales:	Sun, Yi, Jing, Jun, Xu, Huan, Xu, Lingfan, Hu, Hailiang, Tang, Cai, Liu, Shengzhuo, Wei, Qiang, Duan, Ruiqi, Guo, Ju, Yang, Lu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949480/ https://www.ncbi.nlm.nih.gov/pubmed/33692219 http://dx.doi.org/10.1136/jitc-2020-002138

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