Interspecies Differences in Proteome Turnover Kinetics Are Correlated With Life Spans and Energetic Demands

Cells continually degrade and replace damaged proteins. However, the high energetic demand of protein turnover generates reactive oxygen species that compromise the long-term health of the proteome. Thus, the relationship between aging, protein turnover, and energetic demand remains unclear. Here, w...

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Detalles Bibliográficos
Autores principales: Swovick, Kyle, Firsanov, Denis, Welle, Kevin A., Hryhorenko, Jennifer R., Wise, John P., George, Craig, Sformo, Todd L., Seluanov, Andrei, Gorbunova, Vera, Ghaemmaghami, Sina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950207/
https://www.ncbi.nlm.nih.gov/pubmed/33639418
http://dx.doi.org/10.1074/mcp.RA120.002301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950207/
https://www.ncbi.nlm.nih.gov/pubmed/33639418
http://dx.doi.org/10.1074/mcp.RA120.002301

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