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Interspecies Differences in Proteome Turnover Kinetics Are Correlated With Life Spans and Energetic Demands
Cells continually degrade and replace damaged proteins. However, the high energetic demand of protein turnover generates reactive oxygen species that compromise the long-term health of the proteome. Thus, the relationship between aging, protein turnover, and energetic demand remains unclear. Here, w...
Autores principales: | Swovick, Kyle, Firsanov, Denis, Welle, Kevin A., Hryhorenko, Jennifer R., Wise, John P., George, Craig, Sformo, Todd L., Seluanov, Andrei, Gorbunova, Vera, Ghaemmaghami, Sina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950207/ https://www.ncbi.nlm.nih.gov/pubmed/33639418 http://dx.doi.org/10.1074/mcp.RA120.002301 |
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