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Coumestrol mitigates retinal cell inflammation, apoptosis, and oxidative stress in a rat model of diabetic retinopathy via activation of SIRT1

Diabetes-induced oxidative stress is vital in initiating neuronal damage in the diabetic retina, leading to diabetic retinopathy (DR). This study investigates the possible effects of coumestrol (CMS) on streptozotocin (STZ)-induced DR. First, we established a rat model of DR by STZ injection and a c...

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Detalles Bibliográficos
Autores principales: Xu, Yanchao, Zhang, Yusong, Liang, Hongwei, Liu, Xiaomeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950241/
https://www.ncbi.nlm.nih.gov/pubmed/33536350
http://dx.doi.org/10.18632/aging.202467