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Dexmedetomidine reverses MTX-induced neurotoxicity and inflammation in hippocampal HT22 cell lines via NCOA4-mediated ferritinophagy

The incidence of chemotherapy-induced cognitive impairment (CICI) has attracted massive attention. Some studies have demonstrated the neuroprotective effects of dexmedetomidine (DEX). Here, alterations in nuclear receptor coactivator 4 (NCOA4)-mediated ferritinophagy were investigated as the possibl...

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Detalles Bibliográficos
Autores principales: Chen, Jingli, Wang, Juan, Li, Chenxi, Ding, Huang, Ye, Jishi, Xia, Zhongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950253/
https://www.ncbi.nlm.nih.gov/pubmed/33632938
http://dx.doi.org/10.18632/aging.202626