Overexpression of hsa_circ_0002874 promotes resistance of non-small cell lung cancer to paclitaxel by modulating miR-1273f/MDM2/p53 pathway

Background: This study aimed to investigate the aberrant expression of hsa_circ_0002874 in non-small cell lung cancer (NSCLC) and elucidate associated molecular mechanisms that influence apoptosis and induce paclitaxel (PTX) resistance. Methods: Inhibitors were used to downregulate circRNA or miRNA...

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Detalles Bibliográficos
Autores principales: Xu, Jianhao, Ni, Liwei, Zhao, Fenglun, Dai, Xiaoxiao, Tao, Jialong, Pan, Jia, Shi, Aiming, Shen, Zhu, Su, Cunjin, Zhang, Yusong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950269/
https://www.ncbi.nlm.nih.gov/pubmed/33612481
http://dx.doi.org/10.18632/aging.202521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950269/
https://www.ncbi.nlm.nih.gov/pubmed/33612481
http://dx.doi.org/10.18632/aging.202521

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