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USP30 protects against oxygen-glucose deprivation/reperfusion induced mitochondrial fragmentation and ubiquitination and degradation of MFN2

Cerebral ischemia-reperfusion induces mitochondrial fragmentation and dysfunction, which plays a critical role in the subsequent neuronal death and neurological impairment. Protection of mitochondria is an effective strategy to prevent neuronal damage after cerebral ischemia-reperfusion injury. USP3...

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Detalles Bibliográficos
Autores principales: Chen, Chunli, Qin, Haiyun, Tang, Jiayu, Hu, Zhiping, Tan, Jieqiong, Zeng, Liuwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950302/
https://www.ncbi.nlm.nih.gov/pubmed/33609088
http://dx.doi.org/10.18632/aging.202629