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MYCN Drives a Tumor Immunosuppressive Environment Which Impacts Survival in Neuroblastoma
A wide range of malignancies presents MYCN amplification (MNA) or dysregulation. MYCN is associated with poor prognosis and its over-expression leads to several dysregulations including metabolic reprogramming, mitochondria alteration, and cancer stem cell phenotype. Some hints suggest that MYCN ove...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951059/ https://www.ncbi.nlm.nih.gov/pubmed/33718189 http://dx.doi.org/10.3389/fonc.2021.625207 |