Epigenetic Silencing of STAT3-Targeted miR-193a, by Constitutive Activation of JAK/STAT Signaling, Leads to Tumor Progression Through Overexpression of YWHAZ in Gastric Cancer

PURPOSE: The purpose of this study was to identify genes that were epigenetically silenced by STAT3 in gastric cancer. METHODS: MBDcap-Seq and expression microarray were performed to identify genes that were epigenetically silenced in AGS gastric cancer cell lines depleted of STAT3. Cell lines and a...

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Detalles Bibliográficos
Autores principales: Wei, Kuo-Liang, Chou, Jian-Liang, Chen, Yin-Chen, Low, Jie-Ting, Lin, Guan-Ling, Liu, Jing-Lan, Chang, Te-Sheng, Chen, Wei-Ming, Hsieh, Yung-Yu, Yan, Pearlly S., Chuang, Yu-Ming, Lin, Jora M. J., Wu, Shu-Fen, Chiang, Ming-Ko, Li, Chin, Wu, Cheng-Shyong, Chan, Michael W. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951088/
https://www.ncbi.nlm.nih.gov/pubmed/33718136
http://dx.doi.org/10.3389/fonc.2021.575667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951088/
https://www.ncbi.nlm.nih.gov/pubmed/33718136
http://dx.doi.org/10.3389/fonc.2021.575667

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