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Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19

Immune response dynamics in coronavirus disease 2019 (COVID-19) and their severe manifestations have largely been studied in circulation. Here, we examined the relationship between immune processes in the respiratory tract and circulation through longitudinal phenotypic, transcriptomic, and cytokine...

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Detalles Bibliográficos
Autores principales: Szabo, Peter A., Dogra, Pranay, Gray, Joshua I., Wells, Steven B., Connors, Thomas J., Weisberg, Stuart P., Krupska, Izabela, Matsumoto, Rei, Poon, Maya M.L., Idzikowski, Emma, Morris, Sinead E., Pasin, Chloé, Yates, Andrew J., Ku, Amy, Chait, Michael, Davis-Porada, Julia, Guo, Xinzheng V., Zhou, Jing, Steinle, Matthew, Mackay, Sean, Saqi, Anjali, Baldwin, Matthew R., Sims, Peter A., Farber, Donna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951561/
https://www.ncbi.nlm.nih.gov/pubmed/33765436
http://dx.doi.org/10.1016/j.immuni.2021.03.005