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Discovery of Clioquinol and analogues as novel inhibitors of Severe Acute Respiratory Syndrome Coronavirus 2 infection, ACE2 and ACE2 - Spike protein interaction in vitro

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the etiological agent for coronavirus disease 2019 (COVID-19), has resulted in an ongoing pandemic. Presently, there are no clinically approved drugs for COVID-19. Hence, there is an urgent need to accelerate the development of effective...

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Detalles Bibliográficos
Autores principales: Olaleye, Omonike A., Kaur, Manvir, Onyenaka, Collins, Adebusuyi, Tolulope
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951571/
https://www.ncbi.nlm.nih.gov/pubmed/33732940
http://dx.doi.org/10.1016/j.heliyon.2021.e06426