Tet1 is not required for myeloid leukemogenesis by MLL-ENL in novel mouse models

The Ten Eleven Translocation 1 (TET1) gene encodes an epigenetic modifying molecule that is involved in demethylation of 5-methylcytosine. In hematological malignancies, loss-of-function mutations of TET2, which is one of the TET family genes including TET1, are frequently found, while the mutations...

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Detalles Bibliográficos
Autores principales: Ono, Ryoichi, Masuya, Masahiro, Inoue, Naokazu, Shinmei, Makoto, Ishii, Satomi, Maegawa, Yuri, Maharjan, Bishnu Devi, Katayama, Naoyuki, Nosaka, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951824/
https://www.ncbi.nlm.nih.gov/pubmed/33705482
http://dx.doi.org/10.1371/journal.pone.0248425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951824/
https://www.ncbi.nlm.nih.gov/pubmed/33705482
http://dx.doi.org/10.1371/journal.pone.0248425

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