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Effect of conditional deletion of cytoplasmic dynein heavy chain DYNC1H1 on postnatal photoreceptors

Cytoplasmic dynein (dynein 1), a major retrograde motor of eukaryotic cells, is a 1.4 MDa protein complex consisting of a pair of heavy chains (DYNC1H1) and a set of heterodimeric noncatalytic accessory components termed intermediate, light intermediate and light chains. DYNC1H1 (4644 amino acids) i...

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Detalles Bibliográficos
Autores principales: Dahl, Tiffanie M., Reed, Michelle, Gerstner, Cecilia D., Ying, Guoxin, Baehr, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951903/
https://www.ncbi.nlm.nih.gov/pubmed/33705456
http://dx.doi.org/10.1371/journal.pone.0248354