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3-Methyladenine-enhanced susceptibility to sorafenib in hepatocellular carcinoma cells by inhibiting autophagy

As an effective targeted therapy for advanced hepatocellular carcinoma (HCC), sorafenib resistance has been frequently reported in recent years, with the activation of autophagy by cancer cells under drug stress being one of the crucial reasons. Sorafenib treatment could enhance autophagy in HCC cel...

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Detalles Bibliográficos
Autores principales: Zhao, Fangfang, Feng, Guohe, Zhu, Junyao, Su, Zhijun, Guo, Ruyi, Liu, Jiangfu, Zhang, Huatang, Zhai, Yongzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952045/
https://www.ncbi.nlm.nih.gov/pubmed/33395067
http://dx.doi.org/10.1097/CAD.0000000000001032