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Single-molecule view of coordination in a multi-functional DNA polymerase

Replication and repair of genomic DNA requires the actions of multiple enzymatic functions that must be coordinated in order to ensure efficient and accurate product formation. Here, we have used single-molecule FRET microscopy to investigate the physical basis of functional coordination in DNA poly...

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Detalles Bibliográficos
Autores principales: Pauszek, Raymond F, Lamichhane, Rajan, Rajkarnikar Singh, Arishma, Millar, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952088/
https://www.ncbi.nlm.nih.gov/pubmed/33704066
http://dx.doi.org/10.7554/eLife.62046